ISEMPH 2020 – Athens, Georgia

The Sixth Annual Meeting of the International Society for Evolution, Medicine, and Public Health will be in Athens, Georgia, from July 15-18, 2020. ISEMPH 2020 will gather delegates from around the world. It follows in the footsteps of successful previous meetings in Tempe, Arizona; Durham, North Carolina; Groningen, The Netherlands; Park City, Utah; and Zurich, Switzerland. ISEMPH 2020 is profoundly interdisciplinary and emphasizes the multiple interfaces between evolutionary biology and human health in the complementary fields of medicine, evolutionary biology, anthropology, evolutionary psychology, behavioral ecology and epidemiology. The meetings welcome students and clinicians at all stages of professional development.

The 2020 program will include plenary sessions led by some of the world’s leading evolutionary medicine experts including:

Vaughn Cooper, PhD, Professor of Microbiology & Molecular Genetics at the University of Pittsburgh, will speak about “The Roles of Chance, History, and Natural Selection in the Evolution of Pathogenesis and Antimicrobial Resistance.”

Kevin Keel, DVM, PhD, Associate Professor of Pathology, Microbiology & Immunology at the UC Davis School of Veterinary Medicine, will speak about “Urban Wildlife: A One Health Challenge.”

Sudhir Kumar, PhD, Laurel H. Carnell Professor and Director of the Institute of Genomics and Evolutionary Medicine at Temple University, will speak on how “Evolution Informs Genomic Medicine.”

Nina Marano, DVM, MPH, Chief of the Immigrant, Refugee, and Migrant Health Branch, Division of Global Migration and Quarantine, at the Centers for Disease Control and Prevention, will speak about One Health in Action at the CDC: Protecting Health in the United States and Around the World.

Beverly Strassmann, PhD, Professor of Anthropology and Faculty Associate, Institute for Social Research at the University of Michigan, will speak about “Developmental Origins in Evolutionary Perspective: A 20-Year Prospective Cohort Study of the Dogon of Mali.”

Paul Turner, PhD, Rachel Carson Professor of Ecology and Evolutionary Biology at the Yale University School of Medicine, will speak about “Leveraging Evolutionary Trade-Offs and Phage Selection Pressure to Reduce Bacterial Pathogenicity.”

For more information, visit ISEMPH 2020.

COHA Member, Dr. Susan VandeWoude Named Director of CSU One Health Institute

photo Sue VandeWoudeDr. VandeWoude is a professor of comparative medicine as well as associate dean for research in CVMBS.                              Photo: William A. Cotton/CSU Photography

By Lauren Klamm

Dr. Susan VandeWoude, associate dean for research in the Colorado State University College of Veterinary Medicine and Biomedical Sciences, and member of the National Academy of Sciences, has been named the director of the CSU One Health Institute. She will assume full-time duties July 1, 2020, after completing a Fulbright scholarship award.

VandeWoude will lead the institute, which is focused on examining interconnected problems in health, between humans, animals and the environment. Her new role will work to enhance interdisciplinary approaches to gain additional insights into the complex health relationships, said CSU Vice President for Research Alan Rudolph.

“The One Health Institute explores the interfaces and relationships between animals, humans and the environment, recognizing the connectedness of the ecosystem when it comes to disease and other environmental perturbations,” Rudolph explained.

Research on viruses

Between research, teaching and veterinary medicine, VandeWoude has served in a variety of roles at CSU. She became a faculty member in the Department of Microbiology, Immunology, and Pathology in 1991, and served as director of Laboratory Animal Resources from 2007-11. VandeWoude is a professor of comparative medicine as well as associate dean for research in CVMBS.

VandeWoude has specialized in studying immunodeficiency viruses affecting domestic and non-domestic felines that can leave animals vulnerable to other infections. Her discoveries are linked to both animal and ecological concerns and help illustrate the emergence and spread of viruses in humans. Her outstanding work in this area contributed to her election to  the National Academy of Sciences in 2019.

About Sue VandeWoude

VandeWoude completed her bachelor of science at California Institute of Technology and her doctor of veterinary medicine degree at Virginia Maryland Regional College of Veterinary Medicine. After a brief time in clinical veterinary practice, she completed a post-doctoral fellowship in comparative medicine at Johns Hopkins University School of Medicine.

Her post-doctoral research involved characterization of the viral agent associated with Borna Disease Agent. She joined Colorado State University in 1990 and obtained Diplomate status in the American College of Laboratory Animal Medicine in 1991.

About One Health Institute

The One Health Institute grew from initiatives led by Dr. Mark Stetter, dean of the College of Veterinary Medicine and Biomedical Sciences, with assistance from VandeWoude. When One Health activities expanded to other colleges, oversight transferred to the Office of the Vice President for Research. The institute began in 2015 when the Office of the Vice President for Research awarded a total of $360,000 in seed grants to jump-start six promising One Health research projects across campus.

In April 2019, the initiative awarded four grants to teams exploring interrelationships of people, animals and the environment to solve important complex health problems in the Navajo Nation, the dairy industry, Colorado food systems and disease risk in Guatemala.

“I am very excited to bring together and reinvigorate the CSU One Health community, reengage with local partners, collaborate with other CSU centers and institutes with health-related goals, and operationalize ongoing and new initiatives in One Health,” said VandeWoude.

The One Health Institute is housed in Johnson Hall.

Link to article:

2019 Pilot Grant Recipients

1. COHA Bioethics Pilot Final Sarah Moore OSU


Principal investigator:

Sarah Moore, DVM, DACVIM (Neurology)

The Ohio State University

College of Veterinary Medicine


Cheryl London, DVM, PhD, DACVIM (Oncology)

Tufts University

College of Veterinary Medicine

Joan Coates, DVM, MS, DACVIM (Neurology)

University of Missouri, Columbia

College of Veterinary Medicine

Natasha Olby, DVM, PhD, DACIVM (Neurology)

North Carolina State University

College of Veterinary Medicine

Angela McCleary-Wheeler, DVM, PhD, DACVIM (Oncology)

University of Missouri, Columbia

College of Veterinary Medicine


Helen O’Meara, MS, CPIA

Associate Director, IACUC/IBC

Office of Research, Office of Responsible Research Practices

The Ohio State University

Kim Toussant, MBOE, MA, CRA

Director, Office of Responsible Research Practices

Office of Research

The Ohio State University


The Ohio State University

Tufts University

University of Missouri, Columbia

North Carolina State University

Abstract: Veterinary clinical trials are uniquely positioned to contribute substantially to translational science, ultimately benefiting both pets and people. However, no formal guidance exists pertaining to ethical conduct of veterinary trials. As such, individual institutions have established site-specific protocols for approval and monitoring, making a harmonized approach challenging, particularly in an era where multi-site trials are becoming the norm. The work described in this proposal originates from the Clinical Studies Subcommittee and leverages complimentary clinical trial and regulatory expertise from four CTSA One Health Alliance (COHA) hubs

(The Ohio State University, University of Missouri, Tufts, and North Carolina State University) to address several important elements of ethical research that the subcommittee has identified as important opportunities for advancement: subject selection and enrollment, study protocol review and approval, and owner/patient engagement. We will survey the COHA community as a whole to document the current landscape and will then convene a two-day meeting with working groups formed around each key area. Outcomes of the meeting will include a gap analysis focusing on these three areas in the context of NIH’s 8 guiding ethical principles, and a guidance document addressing identified needs and a proposed framework to address them will be distributed across the COHA network for feedback and then published. This guidance document will serve as a blueprint for a planned administrative supplement application [NIH Administrative Supplement for Research on Bioethical

Issues (PA-19-217)] addressing needs identified from gap analysis and network feedback.

Specific Aims: With increasing collaborative initiatives across the landscape of human and veterinary medicine, a unique opportunity exists for comparative medicine that leverages veterinary patients to positively impact translational medicine efforts. However, a major impediment to more broadly engaging the scientific community in the use of spontaneous models is the lack of clear guidance regarding oversight of clinical trials that use client owned animals. While reduced regulatory burden can enhance the pace of science, a lack of guidance or universal protocols opens the veterinary community to scrutiny, particularly when adverse outcomes occur in animals enrolled in veterinary clinical trials. Moreover, the absence of standard processes and procedures has created an environment in which individual institutions have established site-specific protocols for approval and monitoring of clinical research, and as such, harmonizing cross-institutional efforts is challenging. Exempt from federal laws such as the Animal Welfare Act, which was developed to provide ethical standards for the use of animals in laboratory research, ethical considerations relevant to veterinary clinical research now more closely resemble those of human clinical trials. These include the use of healthy client-owned animals in research, enrollment of vulnerable health populations, and historically limited collaboration with community members and partners. Despite an abundance of important bioethical considerations, there are currently no resources providing guidance for the ethical design and conduct of clinical research in companion animals.

The goal of this pilot application, originating from the COHA Clinical Studies Subcommittee and addressing important subcommittee priorities, is to work toward development of structured guidance related to bioethical principles in veterinary clinical research. We will perform a gap analysis centering on

NIH-defined key elements of ethical clinical research in order to identify opportunities and challenges in the veterinary research community that can be transformed into actionable items targeting improved trial rigor and efficiency. This will facilitate enhanced integration of veterinary clinical trials on the translational spectrum while integrating important ethical principles that protect the owner, the patient, and the clinician. Ultimately, we will use this process to develop a draft guidance document detailing proposed solutions and a framework to address the identified gaps will be shared across the COHA community and with the COHA Steering Committee. Input from these groups will further enhance network-wide acceptance of proposed solutions.

CTSA One Health Alliance (COHA) Pilot Grant Program

2. “Advancing One Health through Interprofessional Education in Veterinary Professional Curricula”


Principle Investigator:

Amara H. Estrada, DVM, Diplomate ACVIM (Cardiology), University of Florida

On behalf of the Clinician-Scientist Training Subcommittee of COHA


Amy Blue, Clinical Professor, Associate Vice President for Interprofessional Education – University of Florida, Associate Dean for Educational Affairs, College of Public Health and Health Professions


Ruthanne Chun, Associate Dean for Clinical Affairs and Hospital Director, Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison


Hossein Khalili, Director, Center for Interprofessional Practice and Education (CIPE), University of Wisconsin-Madison, Co-Founder & Co-Lead Interprofessional Research Global, Board Member, Global Confederation for Interprofessional Practice& Education

Executive Board Member, Canadian Interprofessional Health Collaborative


Laura Molgaard, Associate Professor and Senior Associate Dean for Academic and Student Affairs, at the University of Minnesota College of Veterinary Medicine


Brian Sick, Associate Professor, Internal Medicine and Pediatrics, Division Director, General Internal Medicine, Interprofessional Academic Deputy, University of Minnesota AHC


University of Florida

University of Wisconsin-Madison

University of Minnesota


The proposal will support the networking and collaboration of a working group focused on advancing One Health through interprofessional education (IPE) in veterinary professional curricula. Translational medicine cannot be successful without effective working teams of professionals across varied professions. Veterinary medicine, which often provides the access to many translational disease models, is a critical profession to include in One Health translational medicine. Veterinary medicine is also strongly connected to zoonotic disease and plays a critical role in global health. Unfortunately, the current professional training in Veterinary curricula does not include many interprofessional opportunities. One Health, while widely recognized in Veterinary academia, is generally left to faculty to practice and role model for veterinary students. In other health professions, the focus of interprofessional education is primarily on the individual patient healthcare team with little emphasis on the broader concept of One Health. With an IPE curriculum that intentionally provides students an experience of working with even just one other health profession, IPE activities can serve as a gateway to translational science and One Health. Effective implementation of IPE lays the foundation for future clinicians and scientists to participate in the exact endeavors needed for translational medicine. The working group set out in this proposal seeks to facilitate implementation of IPE through the development of One Health focused IPE core competencies. Utilizing a collaborative meeting space and agenda, the working group will bring together IPE and One Health champions from multiple institutions to network and compose the project deliverables.

Specific Aims

Interprofessional Education (IPE) has become a key focus in the curricula of multiple health professions, sometimes including veterinary medicine. It is required in several health professions per accreditation standards (HPAC, 2019). The broad purpose of IPE is to provide educational opportunities between two or more professions that lead to current and future cross collaboration with the objective of improving patient and client care and health outcomes (CAIPE, 2018, WHO, 2010). One of the challenges for implementing IPE programs that include veterinary medicine is understanding the role of the veterinarian in the health team. The One Health initiative, with its focus on interprofessional collaboration, shares many similar themes with IPE and is widely utilized in veterinary medical education. The project outlined in this pilot proposal intends to leverage this relationship in accomplishing three specific aims listed below.

Specific Aim 1: Establish a shared working definition of One Health. One Health has been widely accepted as the next step in the evolution of public health. The initiative recognizes how the health of people, animals and the environment they share is intertwined and the goal of multidisciplinary collaboration is to solve targeted health issues. Veterinary medicine has rightfully stepped up to fulfill its role in this effort with most colleges actively affiliated or even leading their institution’s One Health centers. The challenge, however, is that each institutional definition of One Health is established through their own organizational lens. The University of Florida, for example, incorporates big data in its definition, while the University of Minnesota’s definition focuses more on its global impact. Therefore, the first aim of the project is to establish a shared working definition of One Health in the interprofessional educational context, specifically in the relationship between veterinary medical education and other health professions education

Specific Aim 2: Outline how Interprofessional Education supports the One Health mission. IPE focuses on educational opportunities that bring together different health-related professions to learn with, from and about each other to improve collaboration and quality care. The focus on interprofessional interaction clearly aligns with the broader One Health goals. Working from the established definition from specific aim 1, the project will next identify how IPE supports the goals of One Health. This will provide the foundation for development of plans and initiatives for One Health focused IPE modules, courses, and curricula.

Specific Aim 3: Create an action plan for the development and integration of One Health focused IPE core competencies. IPE can be difficult to implement at any university. The logistical challenges, with different health profession programs on different class schedules, alone create formidable obstacles. The organizational and perception barriers to including IPE in curricula make it difficult to enact at any institution. The objective of this aim is to build upon the previous two aims in developing a set of talking points for IPE champions, in all health professions, to use in proposing and implementing One Health focused IPE initiatives at their university. The creation of these talking points will allow us to disseminate what we have learned (veterinary and non-veterinary) to our colleagues across professions in order to facilitate change management strategies.

3. Effective Branding of the One Health Campaign

CTSA One Health Alliance (COHA) Communication and Collaboration Subcommittee

COHA Pilot Grant Proposal


Personnel (biosketches for Co-PIs attached):

The eight investigators on this proposal already collaborate as members of the COHA Communication and Collaboration Subcommittee.

Co-PI: Gary A. Anderson, DVM, MS, PhD, Professor/Director

Animal Health & Food Safety Institute, Kansas State University *Lead institution

Co-PI: Tracy L. Webb, DVM, PhD, Research Scientist II

Clinical Sciences Department, Colorado State University


Michael O. Childress, DVM, MS, DACVIM (Oncology), Associate Professor

College of Veterinary Medicine, Purdue University

Lisa M. Freeman, DVM, PhD, DACVN, Professor

Cummings School of Veterinary Medicine, Tufts University

Carolyn Henry, DVM, MS, DACVIM (Oncology), Professor, Dean

College of Veterinary Medicine, University of Missouri

Martin H. Moen, Director of Advancement

College of Veterinary Medicine, University of Minnesota

Jorge Piedrahita, MSc, PhD, Professor; Director, Comparative Medicine Institute

College of Veterinary Medicine, North Carolina State University

Shelley C. Rankin, BSc (Hons), PhD, Professor

School of Veterinary Medicine, University of Pennsylvania


Kansas State University

Colorado State University

Purdue University

Tufts University

University of Missouri

University of Minnesota

North Carolina State University

University of Pennsylvania


Despite continued efforts, many healthcare practitioners, scientists, public health officials, and community workers are not aware of the One Health concept and its benefits. One Health activities are most often initiated by veterinarians in academia. In order to increase awareness of the opportunities and benefits of collaborative One Health teams, it is essential to educate and engage the community and human health researchers and providers. Accordingly, we propose to strategically develop a strong message and compelling story to tell that will enhance awareness, knowledge, and value of One Health to a broader audience. The Story Lab in Lenexa, KS, specializes in assisting clients to tell their story by developing plans through a “share, shape, and show” model of communication that has proven to accelerate adoption, which is exactly what is needed to further advance the One Health initiative locally, regionally, and nationally. Working with a highly experienced and effective company will enable the Communication and Collaboration Subcommittee to create the strong and consistent messaging needed to accelerate awareness and adoption of One Health. The Story Lab helps teams create and connect their future state storylines to a clear strategic plan that can be put into action. The team will engage organizations, industry, community members, and researchers to not only develop a strong, compelling message but also a story campaign including story trailers (short videos) and brand-style guides that will enhance awareness, knowledge, and value of One Health. The end result will be storylines created and connected to a clear strategic plan that can be put into action across multidisciplinary teams and universities.

Specific Aims:

Aim 1: Engage Story Lab and jointly develop the One Health “Story”.

A strong, creative One Health message will be developed utilizing a storytelling concept. Story Lab will create the message and facilitate adoption by applying principles of story structure, diffusion on innovation, and behavior change.

COHA Communication and Collaboration co-investigators will provide content and current perspectives while Story Lab will provide expertise, facilitate the development process, and deliver selected communication methods to be used by

COHA members in a manner that can be personalized to individual groups and institutions.

Aim 2: Develop a campaign to launch the One Health “Story”.

A list of target audiences will be developed for sharing and showing the One Health “Story” that will be put into action.

Aim 3: Develop and administer a pre- and post-survey to assess One Health awareness and knowledge following the “Story” campaign.

A survey will be developed for assessing awareness and knowledge pre- and post-campaign launch. The same population will be surveyed both pre- and post-campaign to assess changes in awareness and knowledge of One Health.


2018 Pilot Grant Recipients


Grant Title *PI, Lead Institution/Key Contributors
Enhancing Awareness of One Health: An Inter-Professional Student Collaboration and Strategic Planning Effort *Co-PI Dr. Lisa Freeman, Tufts University
*Co-PI Dr. Tracy L. Webb, Colorado State University
Dr. Michael O. Childress, Purdue University
Dr. Carolyn Henry, University of Missouri
Dr. Debbie Kirchhoff, Kansas State University Olathe
Dr. Michael D. Lairmore, University of California Davis
Dr. Martin H. Moen, University of Minnesota
Dr. Jorge Piedrahita, North Carolina State University
Dr. Shelley C. Rankin, University of Pennsylvania
Translational Research Immersion Program (TRIP) for Veterinary Faculty *Co-PI Dr. Lauren Trepanier, University of Wisconsin-Madison
*Co-PI Dr. Christine Sorkness, University of Wisconsin-Madison
Dr. Dale Bjorling, University of Wisconsin-Madison
Dr. Benjamin Brainard, University of Georgia
Dr. Amara Estrada, University of Florida
Dr. Brian Flesner, University of Missouri
Dr. Eva Furrow, University of Minnesota
Dr. Kelly Hume, Cornell University
Dr. Michael Oglesbee, The Ohio State University
Dr. Natasha Olby, North Carolina State University
Dr. Mark Oyama, University of Pennsylvania
Dr. Rob Rebhun, University of California Davis
Dr. Cynthia Webster, Tufts University
Dr. Kelly Santangelo, Colorado State University

2017 Pilot Grant Recipients

Grant Title *PI, Lead Institution/Key Contributors
Translational Research Summit 2.0: Advancing Team Science *Dr. Lauren Trepanier, University Wisconsin- Madison
Dr. Amara H. Estrada, University of Florida
Dr. Joshua Stern, University of California-Davis
Dr. Kathryn M. Meurs, North Carolina State University
Dr. N. Sydney Moise, Cornell University
Dr. Lisa M. Freeman, Tufts University
Dr. John Rush, Tufts University
Workshop for Advancing One Health Datasets *Dr. Sue VandeWoude, Colorado State University
Dr. Joe Strecker, Colorado State University
Dr. Michael G. Kahn, Colorado State University
Dr. Cheryl London, Tufts University
Dr. Rachel E. Cianciolo, The Ohio State University
Dr. Rebecca Garabed, The Ohio State University
Dr. Gert Breur, Purdue
Dr. Joan Coates, University of Missouri
Improving Translational Resources – Enhancing Visibility and Inter-college Cooperation for Increased Biospecimen Use from Veterinary Academic Biobanks *Dr. Marta Castelhano, Cornell University
Dr. Danika Bannasch, University of California- Davis
Dr. Susan Lana, Colorado State University
Dr. Jonathan Levine, Texas A&M University
Collaborator: Kristy Richards, Cornell University
An Inter-Professional Student Collaboration to Enhance Awareness of One Health *Dr. Lisa M. Freeman, Tufts University
Dr. Benjamin J. Darien, University of Wisconsin- Madison
Dr. Carolyn Henry, University of Missouri
Dr. Jorge Piedrahita, North Carolina State University
Dr. Shelley C. Rankin, University of Pennsylvania
Dr. Tracy L. Webb, Colorado State University

2015 Pilot Grant Recipients

Grant Title *PI, Lead Institution/Key Contributors
Advancing Team Science Through Translational Research Summits *Dr. Lauren Trepanier, University Wisconsin- Madison
Dr. Jon Cheetham, Cornell University
Dr. Anne Avery, Colorado State University
Dr. Rebhun, University of California- Davis
Development of Standard Processes and Procedures for Conducting Translational Clinical Trials in Client Owned Animals

*Dr. Cheryl London, The Ohio State University
Dr. Michael Conzemius, University of Minnesota
Dr. Dottie Brown, University of Pennsylvania
Dr. Erik Wisner, University of California-Davis
Dr. Cynthia Webster, Tufts University

One Health in a Minute *Dr. Lisa M. Freeman, Tufts University
Dr. Maureen Long, University of Florida
Dr. Jorge Piedrahita, North Carolina State University
Dr. Shelley Rankin, University of Pennsylvania
Developing a National Veterinary Biorepository Registry as a Resource for Translational Research *Dr. Susan Lana, Colorado State University
Dr. Kristy Richards, Cornell University
Dr. Marta Castelhano, Cornell University
Dr. Dannika Bannasch, University of California- Davis

Hypertrophic Cardiomyopathy: Collaborating for a Cure video

Hypertrophic Cardiomyopathy (HCM), a heritable cardiac disease affecting 1 in 500 people, is the most important cause of sudden death in young adults and athletes. Cardiologists have made tremendous advances in the diagnosis and treatment of human HCM, and these advances have made their way into veterinary medicine, where they have helped cats. Pet cats also develop HCM but at a much higher rate, affecting 10-15% of cats. While feline patients have been benefiting from advances in human cardiology for many years, the tables are now turning. Hypertrophic cardiomyopathy would provide a highly effective example of the value of One Health for improving both human and animal health.

Also see the accompanying manuscript in Cardiology Research

Woman running with dog

Chronic Pain in Companion Animals video

Chronic pain is a common issue in both companion animals and humans. Pets and humans frequently suffer from similar pain-causing conditions such as bone cancer, diabetes, interstitial cystitis, and osteoarthritis.

Experts on both sides of the One Health spectrum demonstrate how transdisciplinary collaboration, leveraging the stronger validity of naturally occurring disease models, could lead to improved pain control in humans through optimized translational approaches.

Clinical trials in pet dogs and cats to evaluate innovative new drugs or treatments can benefit both animals and humans. Naturally-occurring painful disease in companion animals offers unparalleled opportunities for physicians and veterinarians to collaborate to develop better treatments for all of their patients.

Also see the accompanying manuscript here.