COHA logo

Canine degenerative myelopathy

Canine degenerative myelopathy (DM) is a slowly, progressive adult-onset neurodegenerative disease causing paralysis similar to human amyotrophic lateral sclerosis (ALS – Lou Gehrig’s disease). Canine DM was first described by Averill in 1973 as an insidious, progressive, general proprioceptive (GP) ataxia and upper motor neuron (UMN) spastic paresis of the pelvic limbs ultimately leading to paraplegia and necessitating euthanasia.

Epilepsy

Epilepsy is a chronic neurological condition characterized by unpredictable seizures, and it affects both humans and animals. Management of epilepsy is often challenging, especially with Dravet syndrome and Lennox-Gastaut syndrome, which both manifest as early-onset, treatment-resistant epilepsy in young children.

Equine Ocular Squamous Cell Carcinoma

Ocular squamous cell carcinoma (SCC) is a form of neoplasia (e.g. cancer) affecting the eye of both animals and humans. Ocular SCC is relatively rare in humans, affecting 1 in 1,000,000 people in regions outside of Africa.

Spinal Cord Injury

Intervertebral disc herniation (IVDH)- associated SCI is the most common cause of SCI in pet dogs, with upwards of 20,000 cases managed by veterinary spinal surgeons in the United States every year.